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April 2, 2019
Gilad Mamlok
Chief Financial Officer
Sol-Gel Technologies Ltd.
7 Golda Meir Street
Weizmann Science Park
Ness Ziona, 7403650, Israel
Re: Sol-Gel Technologies Ltd.
Registration Statement on Form F-3
Filed March 28, 2019
File No. 333-230564
Dear Mr. Mamlok:
This is to advise you that we have not reviewed and will not review your
registration
statement.
Please refer to Rules 460 and 461 regarding requests for acceleration.
We remind you
that the company and its management are responsible for the accuracy and
adequacy of their
disclosures, notwithstanding any review, comments, action or absence of action
by the staff.
Please contact Tonya K. Aldave at (202) 551-3601 with any questions.
Sincerely,
Division of
Corporation Finance
Office of
Healthcare & Insurance
cc: Nathan Ajiashvili, Esq.